Histomorphometric parameters of tibia. Significantly greater trabecular separation (F) and osteoclast surface per bone surface (H), lower trabecular bone volume (A), trabecular thickness (B), trabecular number (C), cortical thickness (D), BFR/BS (E), osteoblast surface per bone surface (G) were noted in the smoke-exposed male rats compared to controls. EPF returned the histomorphometric parameters to control levels. Mean ± SD (n = 10 in each group). *P < 0.05 compared to smoke-exposed rats; #
P < 0.05 compared to controls.