| baseline | week 6 | week 12 | week 18 | week 24 | P |
---|---|---|---|---|---|---|
BPI mean severity | 7.26 ± 1.6 | 6.69 ± 1.6 | 6.81 ± 1.8 | 6.33 ± 2-0 | 5.97 ± 2.3** | 0.0028 |
ES | Â | 0.36 | 0.28 | 0.58 | 0.81 | Â |
BPI mean interference with daily activities | 8.13 ± 1.6 | 6.90 ± 2.1** | 6.60 ± 2.4*** | 6.48 ± 2.4*** | 5.93 ± 2.8*** | <0.0001 |
ES | Â | 0.77 | 0.95 | 1.03 | 1.38 | Â |
BDI | 28.0 ± 11.0 | 24.9 ± 13.1 | 21.5 ± 10.4*** | 19.1 ± 9.9*** | 19.3 ± 12.1*** | <0.0001 |
ES | Â | 0.28 | 0.59 | 0.81 | 0.79 | Â |
BDI > 18 (N = 32) | 31.2 ± 9.3 | 27.5 ± 12.7 | 23.2 ± 10.4*** | 20.4 ± 10.1*** | 20.8 ± 12.5*** | <0.0001 |
ES | Â | 0.40 | 0.87 | 1.16 | 1.12 | Â |
HADS-A | 13.9 ± 3.9 | 13.2 ± 4.5 | 12.0 ± 4.5* | 11.9 ± 4.4** | 11.5 ± 5.0** | = 0.0003 |
ES | Â | 0.17 | 0.48 | 0.52 | 0.61 | Â |
HADS-A > 7 (N = 37) | 14.4 ± 3.4 | 13.7 ± 4 | 12.5 ± 4.1* | 12.4 ± 4.0* | 12.0 ± 4.6** | = 0.0008 |
ES | Â | 0.19 | 0.56 | 0.60 | 0.71 | Â |
HADS-D | 12.2 ± 4.6 | 11.5 ± 4.7 | 10.6 ± 4.7 | 10.4 ± 5.0* | 10.2 ± 4.9* | = 0.0061 |
ES | Â | 0.16 | 0.36 | 0.41 | 0.45 | Â |
HADS-D > 7 (N = 34) | 13.3 ± 3.7 | 12.4 ± 4.2 | 11.2 ± 4.5* | 11.0 ± 4.7** | 10.7 ± 4.7** | = 0.0007 |
ES | Â | 0.25 | 0.58 | 0.63 | 0.71 | Â |