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Table 1 Demographic and clinical data of patients at baseline

From: Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study

  (N = 41)
Sex (female/male) 39/2
Age (years) (22-63)
(range and mean ± s.d.) 48 ± 10
Illness duration from diagnosis (years) (1-19)
(range and mean ± s.d.) 46 ± 4.1
Most frequent comorbidities [N (%)]:  
Temporomandibular dysfunction 30 (73)
Migraine 19 (46.3)
Irritable bowel syndrome 13 (32)
Chronic fatigue syndrome 7 (17.9)
Thyroid disease 7 (17.9)
Rheumathoid arthritis 9 (23.1)
Previous pharmacological treatments [N (%)]:  
Paracetamol 22 (53.6)
NSAIDs 27 (65.8)
Tramadol 12 (29.3)
Benzodiazepines 25 (60.9)
Antidepressants 19 (46.3)
Anticonvulsants: 3 (7.3)
pregabalin/gabapentin 1 (2.4)
Non-pharmacological therapies [N (%)]  
Tai Chi 2 (4.9)
Swimming pool 2 (4.9)
Ozone therapy 1 (2.4)
Yoga 1 (2.4)
Physiotherapy 1 (2.4