Table 8 Kinases regulated in human tendinopathy
Gene Symbol | Description | pValue | q-value | Fold Change |
|---|---|---|---|---|
ABL2 | v-abl Abelson leukemia viral oncogene homolog 2 | 4.79E-03 | 7.83E-03 | 31.0 |
BMPR2 | Bone morphogenetic protein receptor, type II | 4.10E-03 | 7.83E-03 | 27.0 |
CAV2 | Caveolin 2 | 1.22E-02 | 1.44E-02 | 43.0 |
CDK6 | Cyclin-dependent kinase 6 | 1.37E-02 | 1.53E-02 | 24.0 |
CSNK1D | Casein kinase 1, delta | 5.21E-03 | 8.13E-03 | 19.0 |
CSNK1G1 | Casein kinase 1, gamma 1 | 8.18E-03 | 1.03E-02 | 40.0 |
DCLK1 | Doublecortin-like kinase 1 | 3.78E-03 | 7.83E-03 | 28.0 |
EML4 | Echinoderm microtubule associated protein like 4 | 9.69E-04 | 3.15E-03 | 41.0 |
EPS8 | Epidermal growth factor receptor substrate 8 | 1.96E-04 | 1.67E-03 | 9.0 |
FGFR1 | Fibroblast growth factor receptor 1 | 5.64E-03 | 8.46E-03 | 1.7 |
ILK | Integrin-linked kinase | 1.00E-04 | 1.67E-03 | 1.6 |
JAK3 | Janus kinase 3 | 4.62E-03 | 7.83E-03 | 1.8 |
KIAA0220 | PI-3-kinase-related kinase SMG-1 | 2.70E-03 | 7.02E-03 | 1.6 |
KIAA0999 | KIAA0999 protein | 1.62E-03 | 4.86E-03 | 2.1 |
MAP3K2 | Mitogen-activated protein kinase kinase kinase 2 | 4.82E-03 | 7.83E-03 | 1.8 |
MAP4K5 | Mitogen-activated protein kinase kinase kinase 5 | 1.31E-02 | 1.50E-02 | 1.9 |
MAPK8 | Mitogen-activated protein kinase 8 | 1.42E-02 | 1.54E-02 | 2.0 |
NAGK | N-acetylglucosamine kinase | 4.16E-03 | 7.83E-03 | 1.8 |
PALM2-AKAP2 | A kinase (PRKA) anchor protein 2 | 2.31E-02 | 2.37E-02 | 1.9 |
PANK2 | Pantothenate kinase 2 | 6.39E-04 | 2.67E-03 | 1.6 |
PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.35E-04 | 1.67E-03 | 1.8 |
PDLIM5 | PDZ and LIM domain 5 | 8.94E-03 | 1.09E-02 | 1.9 |
PFTK1 | PFTAIRE protein kinase 1 | 4.74E-03 | 7.83E-03 | 1.6 |
PGAM1 | Phosphoglycerate mutase 1 (brain) | 4.81E-04 | 2.35E-03 | 1.6 |
PI4K2B | Phosphatidylinositol 4-kinase type 2 beta | 7.80E-03 | 1.02E-02 | 1.7 |
PIK3C2A | Phosphoinositide-3-kinase, class 2, alpha | 2.28E-02 | 2.37E-02 | 1.5 |
PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase, Iia | 7.52E-04 | 2.67E-03 | 1.5 |
PRKAA1 | Protein kinase, AMP-activated, alpha 1 | 5.32E-02 | 5.32E-02 | 1.7 |
PRKD1 | Protein kinase D1 | 7.86E-03 | 1.02E-02 | 1.8 |
PTK9 | Twinfilin, actin-binding protein, homolog 1 | 1.62E-04 | 1.67E-03 | 1.7 |
RIPK2 | Receptor-interacting serine-threonine kinase 2 | 1.84E-03 | 5.11E-03 | 1.6 |
RIPK5 | Receptor interacting protein kinase 5 | 5.91E-03 | 8.53E-03 | 1.7 |
SGMS2 | Sphingomyelin synthase 2 | 3.38E-03 | 7.76E-03 | 2.3 |
SHC1 | Src homology 2 domain containing protein 1 | 2.99E-04 | 1.67E-03 | 1.7 |
SOCS3 | Suppressor of cytokine signaling 3 | 3.07E-03 | 7.48E-03 | 1.7 |
SSA2 | TROVE domain family, member 2 | 2.72E-04 | 1.67E-03 | 1.6 |
TAOK1 | TAO kinase 1 | 1.51E-04 | 1.67E-03 | 1.7 |
TRIM27 | Tripartite motif-containing 27 | 6.94E-04 | 2.67E-03 | 1.6 |
TTN | Titin | 6.67E-03 | 9.29E-03 | 0.2 |