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Table 3 SNPs frequencies and logistic regression results for the non-union status.

From: Genetic predisposition to fracture non-union: a case control study of a preliminary single nucleotide polymorphisms analysis of the BMP pathway

Gene SNP Genotypes Group A
(non-union)
Group B
(union)
Age unadjusted Age unadjusted Age adjusted Age adjusted
      OR p OR p
   C/C 20 13 1.00   1.00  
  rs4811822 C/T 26 27 0.63 0.30 0.57 0.23
   T/T 16 7 1.49 0.49 1.29 0.67
   C/C 17 12 1.00   1.00  
  rs4811823 C/T 27 27 0.71 0.45 0.61 0.31
BMP-7   T/T 18 8 1.59 0.42 1.36 0.60
   A/A 25 12 1.00   1.00  
  rs1475000 G/A 28 28 0.48 0.10 0.48 0.10
   G/G 9 7 0.62 0.43 0.70 0.57
   A/A 27 15 1.00   1.00  
  rs186659 G/A 27 26 0.58 0.19 0.58 0.21
   G/G 8 6 0.74 0.63 0.80 0.73
   A/A 5 6 1.00   1.00  
  rs1005464 G/A 21 11 2.29 0.24 1.90 0.38
   G/G 36 30 1.44 0.58 1.13 0.85
   A/A 11 9 1.00   1.00  
BMP-2 rs235768 T/A 31 24 1.06 0.92 1.10 0.86
   T/T 20 14 1.17 0.78 1.34 0.62
   A/A 8 7 1.00   1.00  
  rs235764 G/A 24 13 1.62 0.44 1.67 0.42
   G/G 30 27 0.97 0.96 1.21 0.76
   A/A 11 4 1.00   1.00  
  rs1442828 G/A 33 21 0.57 0.39 0.60 0.45
   G/G 18 22 0.30 0.07 0.28 0.06
   A/A 16 19 1.00   1.00  
NOG rs1372857 G/A 30 24 1.48 0.37 1.63 0.27
   G/G 16 4 4.75 0.02 4.56 0.02
   G/G 10 10 1.00   1.00  
  rs9915822 G/T 29 27 1.07 0.89 1.28 0.65
   T/T 23 10 2.30 0.16 2.26 0.17
   C/C 1 5 1.00   1.00  
  rs2053423 C/T 25 20 6.25 0.11 7.74 0.09
   T/T 36 22 8.18 0.05 10.27 0.04
   C/C 23 20 1.00   1.00  
  rs2119261 C/T 34 21 1.41 0.41 1.41 0.41
   T/T 5 6 0.72 0.64 1.00 0.99
   C/C 36 22 1.00   1.00  
SMAD6 rs2119260 C/T 25 21 0.73 0.43 0.73 0.45
   T/T 1 4 0.15 0.10 0.11 0.07
   A/A 2 1 1.00   1.00  
  rs3934907 C/A 18 11 0.82 0.88 0.85 0.90
   C/C 42 35 0.60 0.68 0.62 0.71
   C/C 22 16 1.00   1.00  
  rs3934908 C/T 30 24 0.91 0.82 0.95 0.92
   T/T 10 7 1.04 0.95 1.05 0.93
  1. [Logistic regression results of genotypes for non-union status: p: p- value, OR: odds ratios]