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Table 3 SNPs frequencies and logistic regression results for the non-union status.

From: Genetic predisposition to fracture non-union: a case control study of a preliminary single nucleotide polymorphisms analysis of the BMP pathway

Gene

SNP

Genotypes

Group A

(non-union)

Group B

(union)

Age unadjusted

Age unadjusted

Age adjusted

Age adjusted

     

OR

p

OR

p

  

C/C

20

13

1.00

 

1.00

 
 

rs4811822

C/T

26

27

0.63

0.30

0.57

0.23

  

T/T

16

7

1.49

0.49

1.29

0.67

  

C/C

17

12

1.00

 

1.00

 
 

rs4811823

C/T

27

27

0.71

0.45

0.61

0.31

BMP-7

 

T/T

18

8

1.59

0.42

1.36

0.60

  

A/A

25

12

1.00

 

1.00

 
 

rs1475000

G/A

28

28

0.48

0.10

0.48

0.10

  

G/G

9

7

0.62

0.43

0.70

0.57

  

A/A

27

15

1.00

 

1.00

 
 

rs186659

G/A

27

26

0.58

0.19

0.58

0.21

  

G/G

8

6

0.74

0.63

0.80

0.73

  

A/A

5

6

1.00

 

1.00

 
 

rs1005464

G/A

21

11

2.29

0.24

1.90

0.38

  

G/G

36

30

1.44

0.58

1.13

0.85

  

A/A

11

9

1.00

 

1.00

 

BMP-2

rs235768

T/A

31

24

1.06

0.92

1.10

0.86

  

T/T

20

14

1.17

0.78

1.34

0.62

  

A/A

8

7

1.00

 

1.00

 
 

rs235764

G/A

24

13

1.62

0.44

1.67

0.42

  

G/G

30

27

0.97

0.96

1.21

0.76

  

A/A

11

4

1.00

 

1.00

 
 

rs1442828

G/A

33

21

0.57

0.39

0.60

0.45

  

G/G

18

22

0.30

0.07

0.28

0.06

  

A/A

16

19

1.00

 

1.00

 

NOG

rs1372857

G/A

30

24

1.48

0.37

1.63

0.27

  

G/G

16

4

4.75

0.02

4.56

0.02

  

G/G

10

10

1.00

 

1.00

 
 

rs9915822

G/T

29

27

1.07

0.89

1.28

0.65

  

T/T

23

10

2.30

0.16

2.26

0.17

  

C/C

1

5

1.00

 

1.00

 
 

rs2053423

C/T

25

20

6.25

0.11

7.74

0.09

  

T/T

36

22

8.18

0.05

10.27

0.04

  

C/C

23

20

1.00

 

1.00

 
 

rs2119261

C/T

34

21

1.41

0.41

1.41

0.41

  

T/T

5

6

0.72

0.64

1.00

0.99

  

C/C

36

22

1.00

 

1.00

 

SMAD6

rs2119260

C/T

25

21

0.73

0.43

0.73

0.45

  

T/T

1

4

0.15

0.10

0.11

0.07

  

A/A

2

1

1.00

 

1.00

 
 

rs3934907

C/A

18

11

0.82

0.88

0.85

0.90

  

C/C

42

35

0.60

0.68

0.62

0.71

  

C/C

22

16

1.00

 

1.00

 
 

rs3934908

C/T

30

24

0.91

0.82

0.95

0.92

  

T/T

10

7

1.04

0.95

1.05

0.93

  1. [Logistic regression results of genotypes for non-union status: p: p- value, OR: odds ratios]