Figure 4

Spearman's rho correlations between changes in cytokines (Figure 4a) or changes in extra-and intra-cellular Hsp (Figure 4b) and changes in muscle parameters (raw data as well as results corrected by kg body weight and by kg lean body mass). Significant correlations with p < 0.05 (two-sided) are indicated in red when positive, in blue when negative. Serum levels of cytokines and Hsp were measured at 6 follow-up time-points (changes to baseline indicated by 6 rectangles for each cytokine in each column). Intracellular Hsp were measured at 5 follow-up time-points (changes to baseline indicated by 5 rectangles for each). Muscle parameters were evaluated at 3 follow-up time-points. Correlations were computed between early changes (first days) in cytokines or Hsp and changes in muscle parameters at week 1 and 2. When correlations with these early changes were significant, white numbers in the corresponding rectangle indicate the corresponding time-point of the concerned muscle parameter. The lower three rectangles indicate the concomitant changes compared to baseline at weeks 1, 2 and 3 for both parameters concerned.