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Table 3 Definitions of OA in the cohort studies included in EPOSA

From: European Project on Osteoarthritis (EPOSA): methodological challenges in harmonization of existing data from five European population-based cohorts on aging

Cohort
  ActiFE ProVA LASA Peñagrande HCS
Self-reported OA
Knee - Pain or difficulty moving the knees in the last year? Positive if yes for > 1 month. Do you have OA?
If yes: Would you please tell me if you have complaints of the knee?
- -
Hip - Pain or difficulty moving the hips in the last year? Positive if yes for > 1 month. Do you have OA?
If yes: Would you please tell me if you have complaints of the hip?
- -
Hand - Pain or difficulty moving the hands in the last year? Positive if yes for > 1 month. Do you have OA?
If yes: Would you please tell me if you have complaints of the fingers or hand/wrist?
- -
Non-specific - Positive if "yes" on any of the above Do you have OA? Have you had pains in the joints or bones?
Did you visit a doctor for this problem? Positive if yes on both questions.
-
Clinical OA
Knee - Judgement by physician based on physical examination and information from medical records - - Told by doctor to have knee OA
Hip - Judgement by physician based on physical examination and information from medical records - - -
Hand - Judgement by physician based on physical examination and information from medical records - - Combination of observed Heberdens nodes by trained nurse and self-reported hand pain.
Non-specific Has a doctor ever told you that you have or had OA/arthritis? Positive if "yes" on any of the above General practitioners questionnaire: Has your patient been diagnosed with OA? Diagnosis in general practitioners' records Positive if "yes" on any of the above
Radiographic OA
Knee - JSN (K&L ≥ 2) + osteophytes - - JSN (K&L ≥ 2) + osteophytes
Hip -   - - -
Hand - DIP, PIP of digits 2-3, and CMC of digit 1:
JSN (K&L ≥ 2) + osteophytes
- - DIP, PIP, CMC of digits 2-5, and IP:
JSN (K&L ≥ 2) + osteophytes
  1. ActiFE: study on Activity and Function in the Elderly in Ulm, ProVA: Progetto Veneto Anziani, LASA: Longitudinal Aging Study Amsterdam, Peñagrande: Ageing in Peñagrande, HCS: Hertfordshire Cohort Study, DIP: distal interphalangeal joint, PIP: proximal interphalangeal joint, CMC: carpo-metacarpal joint, IP: interphalangeal joint, K&L: Kellgren & Lawrence grading.
  2. In ProVA., all x-rays were taken at the time of the clinic visit, at the same hospital using the same radiographic equipment with standardized procedures, focus to film distance 100 cm, 55 kV, 8 mA/s. Anteroposterior x-ray of the hip, and weight-bearing anteroposterior and lateral x-rays of both extended knees were performed in standing position. Standard posterior-anterior radiographs of both hands with palm flat and fingers straight were performed.
  3. In HCS, weight bearing anterior-posterior and lateral semi-flexed radiographs of both knees were taken at the same hospital using the same radiographic equipment; a standard tube to film distance of 100|cm was used. Radiographs were performed at a median duration of 6|months (interquartile range (IQR) 4.8-7.2) after the clinic visit. Using the same equipment, anterior-posterior hand radiographs were obtained, with the hand placed as flat as possible.