Table 3 Demographics of the study population and serum levels of enzyme markers grouped by radiological severity (Kellgren/Lawrence Score) and distribution of the haplogroups H, U and J in the 3 radiographic groups
| Â | Healthy controls (n = 77) | OA patients (n = 73) | Â | Â | ||||
|---|---|---|---|---|---|---|---|---|
Mean age (range) | 66.01 years-old (42-94) | 67.74 years-old (51-95) | Â | Â | ||||
Females/Males | 39 females/38 males | 52 females/21 males | Â | Â | ||||
Haplogroups | Group A (n = 77) K/L grade 0 and I | Group B (n = 47) K/L grade II and III | Group C (n = 24) K/L grade IV | Â | Â | |||
Haplogroup H, n(%) | 25 (32.5) | 18 (38.3) | 7 (29.2) | Â | Â | |||
Haplogroup U, n(%) | 25 (32.5) | 12 (25.5) | 13 (54.2) | Â | Â | |||
Haplogroup J, n(%) | 27 (35) | 17 (36.2) | 4 (16.7) | Â | Â | |||
Markers | Mean (SD) | Median | Mean (SD) | Median | Mean (SD) | Median | J-T | p* |
SOD2 (ng/mL) | 20.83 (30.81) | 13.50 | 35.75 (10.44) | 35.02 | 38.10 (12.74) | 39.23 | 7.796 | < 0.001** |
Catalase (ng/mL) | 14.50 (27.68) | 5.03 | 22.82 (42.49) | 8.56 | 20.58 (38.87) | 8.00 | 1.227 | 0.220 |