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Table 2 Histopathologic grading system

From: Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model

Parameter & Grade

Description

Articular cartilage structure

 

0 - 10 (30)

0 = normal, 10 = complete loss to subchondral bone

Reduction of articular cartilage matrix staining

 

0

None

1

Mild

2

Moderate

3

Severe

Presence of osteophytes

 

0

None

1

Cartilage \ connective tissue

2

Mainly cartilage\ some bone formation

3

Mainly bone formation

Subchondral bone plate thickening

 

0

None

1

Mild

2

Moderate

3

Severe