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Table 2 Histopathologic grading system

From: Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model

Parameter & Grade Description
Articular cartilage structure  
0 - 10 (30) 0 = normal, 10 = complete loss to subchondral bone
Reduction of articular cartilage matrix staining  
0 None
1 Mild
2 Moderate
3 Severe
Presence of osteophytes  
0 None
1 Cartilage \ connective tissue
2 Mainly cartilage\ some bone formation
3 Mainly bone formation
Subchondral bone plate thickening  
0 None
1 Mild
2 Moderate
3 Severe