(a) left antebrachiocarpal joint after 9 weeks of OA induction and 6 month of no treatment showing severe articular surface degeneration affecting the 1: ulnar carpal bone, 2: intermediate carpal bone and 3: radial carpal bone. Notice the degenerative line marked by the arrow; (b) right antebrachiocarpal joint after 9 weeks of OA induction and 6 month of MSCs treatment showing improved articular surface. Notice the partial degenerative areas marked by the arrows; (c) left untreated joint of group-I after 2 month follow-up and (d) right treated joint; (e) untreated joint of group-II after 6 month follow-up (f) treated joints. Arrows indicates areas of degeneration. Compare left images (non-cell-treated) with the contralateral (cell-treated) ones.