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Table 6 Characteristics of studies investigating whole blood levels of cytokines in FMS patients.

From: Systematic review with meta-analysis: cytokines in fibromyalgia syndrome

Author, yr.
Diagnosis criteria
N patients/controls a) Material
b) Methods
c) Investigated targets
Results Modified CEBM
level
NOS W-MeQS
Üçeyler, 2006
ACR
26/40 a) serum; whole blood
b) qRT-PCR;
ELISA
c) IL-2, IL-4, IL-8, IL-10, TNF, TGF- β1
In FMS compared to controls:
IL-2 ↔
IL-4
IL-8 ↔
IL-10
TGF-β1 ↔
TNF ↔
3d 4 0.8
  1. Abbreviations:
  2. ACR: American College of Rheumatology; CEMB: Center of Evidence Based Medicine; ELISA: enzyme linked immunosorbent assay; FMS: fibromyalgia syndrome; IL: interleukin; NOS: Newcastle Ottawa Scale; qRT-PCR: quantitative real-time PCR; W-MeQS: Würzburg Methodological Quality Score; yr: year
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