Table 6 Characteristics of studies investigating whole blood levels of cytokines in FMS patients.
From: Systematic review with meta-analysis: cytokines in fibromyalgia syndrome
Author, yr. Diagnosis criteria | N patients/controls | a) Material b) Methods c) Investigated targets | Results | Modified CEBM level | NOS | W-MeQS |
|---|---|---|---|---|---|---|
Üçeyler, 2006 ACR | 26/40 | a) serum; whole blood b) qRT-PCR; ELISA c) IL-2, IL-4, IL-8, IL-10, TNF, TGF- β1 | In FMS compared to controls: IL-2 ↔ IL-4 ⇓ IL-8 ↔ IL-10 ⇓ TGF-β1 ↔ TNF ↔ | 3d | 4 | 0.8 |