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Table 5 Effects of CsA on the mechanical parameters of the femoral neck

From: Effects of cyclosporin-a on rat skeletal biomechanical properties

 

Baseline

(n = 8)

Control

(n = 12)

1.5 mg CsA

(n = 11)

7.5 mg CsA

(n = 9)

Ultimate force (N)

59.3 ± 11.1

70.4 ± 7.2

62.9 ± 13.2

54.9 ± 14.8*

Stiffness (N/mm)

108.4 ± 23.1

115.0 ± 21.3

103.3 ± 20.2

105.6 ± 26.8

Energy absorption (mJ)

31.0 ± 10.4

30.3 ± 7.0

28.8 ± 11.1

27.9 ± 15.5

Ultimate stress (GPa)

0.178 ± 0.016

0.196 ± 0.010

0.175 ± 0.033

0.135 ± 0.026**

Young's modulus (Gpa)

2.25 ± 0.47

2.37 ± 0.39

2.08 ± 0.54

1.67 ± 0.55**

  1. Data are expressed as means ± SD. Compared with the control group, p < 0.05 *, p < 0.01 **.