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Table 4 Effects of CsA on the mechanical parameters of the middle femurs

From: Effects of cyclosporin-a on rat skeletal biomechanical properties

 

Baseline

(n = 8)

Control

(n = 12)

1.5 mg CsA

(n = 11)

7.5 mg CsA

(n = 9)

Ultimate force (N)

112.7 ± 19.1

139.9 ± 23.1

128.6 ± 22.1

131.8 ± 20.3

Stiffness (N/mm)

317.6 ± 87.4

423.6 ± 95.3

347.5 ± 96.4

396.6 ± 89.8

Energy absorption (mJ)

20.1 ± 4.5

23.6 ± 5.4

24.7 ± 5.4

22.9 ± 4.8

Ultimate stress (GPa)

0.098 ± 0.020

0.101 ± 0.016

0.101 ± 0.013

0.096 ± 0.016

Young's modulus (Gpa)

9.9 ± 2.5

10.9 ± 2.5

9.2 ± 1.5

9.6 ± 2.3

Energy absorption (mJ/mm3)

0.49 ± 0.08

0.46 ± 0.07

0.53 ± 0.14

0.47 ± 0.08

  1. Data are expressed as means ± SD.