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Table 2 The VAS pain scales of Placebo and Hyalgan treatment groups on the 50-foot walking test

From: Intra-articular injections of sodium hyaluronate (Hyalgan®) in osteoarthritis of the knee. a randomized, controlled, double-blind, multicenter trial in the asian population

Week (W) Hyalgan® (n = 100) VAS (mm) Placebo (n = 98) VAS (mm) p value
Baseline (W0) 47.85 ± 10.76 45.15 ± 9.75 0.066
W25 17.00 ± 14.32 21.53 ± 15.69 0.035*
Change from W0 to W1 9.9 ± 12.33 7.55 ± 8.95 0.127
Change from W0 to W5 24.75 ± 12.66 20.41 ± 15.38 0.026
Change from W0 to W13 27.27 ± 14.97 24.01 ± 16.95 0.076
Change from W0 to W25 (Primary Outcome) 30.85 ± 14.16 23.62 ± 16.38 0.002**
  1. VAS pain scales were shows as mean ± SD.
  2. *P < 0.05, **P < 0.01, indicated significantly different between treatment groups.