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Table 2 The VAS pain scales of Placebo and Hyalgan treatment groups on the 50-foot walking test

From: Intra-articular injections of sodium hyaluronate (Hyalgan®) in osteoarthritis of the knee. a randomized, controlled, double-blind, multicenter trial in the asian population

Week (W)

Hyalgan® (n = 100) VAS (mm)

Placebo (n = 98) VAS (mm)

p value

Baseline (W0)

47.85 ± 10.76

45.15 ± 9.75

0.066

W25

17.00 ± 14.32

21.53 ± 15.69

0.035*

Change from W0 to W1

9.9 ± 12.33

7.55 ± 8.95

0.127

Change from W0 to W5

24.75 ± 12.66

20.41 ± 15.38

0.026

Change from W0 to W13

27.27 ± 14.97

24.01 ± 16.95

0.076

Change from W0 to W25 (Primary Outcome)

30.85 ± 14.16

23.62 ± 16.38

0.002**

  1. VAS pain scales were shows as mean ± SD.
  2. *P < 0.05, **P < 0.01, indicated significantly different between treatment groups.