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Table 4 Patients characteristics and symptomatic DVT

From: IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics

 

DVD(-)

DVT(+)

 

Characteristics

n = 318

n = 56

p

Age

68.2 ± 11.6

( 25-90 )

74.5 ± 7.8

(45-86)

<0.00001

   Age≧75 yr

106

 

32

 

0.001

   Age < 75 yr

212

 

24

  

Gender(male/female)

60/258

 

5/51

 

0.070

BMI(Kg/m2)

24.7 ± 4.2

(13.7-41.4)

25.8 ± 3.8

(20.1-35.1)

0.088

   BMI≧30

37

 

10

 

0.195

   BMI < 30

281

 

46

  

Risk factors

176(55.3%)

 

38(67.9%)

 

0.081

TKA/THA

125/193

 

35/21

 

0.001

OA/RA

273/46

 

48/7

 

0.697

Seroconvertion of IgG-class Anti-PF4/heparin Ab

54(17.0%)

 

20(35.7%)

 

0.001

Treatment

     

   UFH

89

(27.7%)

16

(28.6%)

0.890

   LMWH

81

(25.5%)

14

(25.0%)

0.940

   Fondaparinux

73

(23.0%)

8

(14.3%)

0.146

   Others

37

(11.6%)

13

(23.2%)

 

Aspirin

31

(9.7%)

12

(21.4%)

 

Warfarin

5

(1.6%)

0

  

Cilostazol

26

(8.2%)

11

(19.6%)

 

   No medication

39

(12.3%)

5

(8.9%)

0.475

  1. Abbreviations: DVT; deep vein thrombosis; BMI; body mass index, TKA; total knee arthroplasty, THA; total hip arthroplasty, OA; osteoarthritis, RA; rheumatoid arthritis, UFH; unfractionated heparin, LMWH; low-molecular weight heparin