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Table 3 Analysis of IgG-class anti-PF4/heparin antibody seroconversion rate

From: IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics

THA/TKA drug No. patients No. seroconversion(%) Total(%)
THA UFH 60 17(28.3) 30(14.0)
  LMWH 64 4(6.3)*  
  Fondaparinux 49 4(8.2)**  
  others 41 5(12.2)  
TKA UFH 44 17(38.6) 44(27.5)****
  LMWH 31 5(16.1)***  
  Fondaparinux 32 8(25.0)  
  others 53 14(26.4)  
  1. Abbreviations: TKA; total knee arthroplasty, THA; total hip arthroplasty, UFH; unfractionated heparin, LMWH; low-molecular weight heparin, *p = 0.001 versus UFH, **p = 0.008 versus UFH, ***p = 0.035 versus UFH, ****p = 0.001 versus THA