IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics

Table 3 Analysis of IgG-class anti-PF4/heparin antibody seroconversion rate

THA/TKA	drug	No. patients	No. seroconversion(%)	Total(%)
THA	UFH	60	17(28.3)	30(14.0)
	LMWH	64	4(6.3)*
	Fondaparinux	49	4(8.2)**
	others	41	5(12.2)
TKA	UFH	44	17(38.6)	44(27.5)****
	LMWH	31	5(16.1)***
	Fondaparinux	32	8(25.0)
	others	53	14(26.4)

Abbreviations: TKA; total knee arthroplasty, THA; total hip arthroplasty, UFH; unfractionated heparin, LMWH; low-molecular weight heparin, *p = 0.001 versus UFH, **p = 0.008 versus UFH, ***p = 0.035 versus UFH, ****p = 0.001 versus THA

ISSN: 1471-2474