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Table 1 Patients characteristics

From: IgG-class anti-PF4/heparin antibodies and symptomatic DVT in orthopedic surgery patients receiving different anti-thromboembolic prophylaxis therapeutics

Characteristics

THA

TKA

p

 

n = 214

n = 160

 

Age

65.6 ± 11.7

(25-90)

73.9 ± 8.9

(30-89)

<0.00001

   Age≧75 yr

49

 

89

 

<0.00001

   Age < 75 yr

165

 

71

  

Gender(male/female)

34/180

 

31/129

 

0.379

BMI(Kg/m2)

24.1 ± 3.8

(15.1-37.7)

25.9 ± 4.3

(13.7-41.4)

<0.00001

   BMI≧30

17

 

30

 

0.002

   BMI < 30

197

 

130

  

Risk factors

102/214

(47.7%)

112/160

(70.0%)

<0.00001

OA/RA

192/22

 

129/31

 

0.013

Seroconvertion of IgG-class Anti-PF4/heparinAb

30/214

(14.0%)

44/160

(27.5%)

0.001

Treatment

     

   UFH

60/214

(28.0%)

44/160

(27.5%)

0.909

   LMWH

64/214

(29.9%)

31/160

(19.4%)

0.021

   Fondaparinux

49/214

(22.9%)

32/160

(20.0%)

0.501

   Others

21/214

(9.8%)

29/160

(18.1%)

0.019

Aspirin

16/214

(7.5%)

27/160

(16.9%)

 

Warfarin

4/214

(1.9%)

1/160

(0.6%)

 

Cilostazol

14/214

(6.5%)

23/160

(14.4%)

 

   No medication

20/214

(9.3%)

24/160

(15.0%)

0.093

  1. Abbreviations: BMI; body mass index, TKA; total knee arthroplasty, THA; total hip arthroplasty, OA; osteoarthritis, RA; rheumatoid arthritis, UFH; unfractionated heparin, LMWH; low-molecular weight heparin