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Table 2 Within-Region Spearman Coefficients (95% Confidence Intervals) Among Baseline BML and Cartilage Parameters in the Index Compartment

From: Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss

 

Femur BML Volume: Baseline

(n = 40)

Tibia BML Volume: Baseline

(n = 37)

Femur BML Volume: Change

(n = 41)

Tibia BML Volume: Change

(n = 39)

Baseline

    

   Cartilage Volume

-0.06 (-0.37, 0.25)

-0.31 (-0.57, 0.02)

-0.06 (-0.37, 0.25)

-0.08 (-0.39, 0.24)

   Cartilage Thickness

0.02 (-0.30, 0.33)

-0.37 (-0.62, -0.05)

-0.12 (-0.42, 0.19)

-0.02 (-0.33, 0.30)

   Full Thickness Cartilage Lesion Area

0.33 (0.02, 0.58)

0.63 (0.38, 0.79)*

-0.06 (-0.36, 0.26)

-0.03 (-0.34, 0.29)

2-year Longitudinal Change

    

   Cartilage Volume

0.03 (-0.29, 0.34)

0.16 (-0.18, 0.46)

-0.10 (-0.39, 0.22)

0.32 (0.00, 0.58)

   Cartilage Thickness

-0.11 (-0.41, 0.21)

-0.13 (-0.43, 0.21)

-0.15 (-0.43, 0.17)

0.04 (-0.28, 0.35)

   Full Thickness Cartilage Lesion Area

0.48 (0.20, 0.69)*

0.43 (0.12, 0.66)

0.08 (-0.23, 0.38)

-0.18 (-0.47, 0.14)

  1. * statistically significant finding after Bonferroni corrections (24 multiple comparisons; p < .002; see Additional File 1 for scatter plots).