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Table 1 Median (95% CI) Baseline and Longitudinal Changes in Approximate BML Volume

From: Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss

Region

Baseline BML Volume (cm3)

BML Volume Change (cm3)

Spearman Correlation (95% CI):

Baseline to Longitudinal Change

Index Femur (n = 76)

4.2 (2.5 to 11.5)

0.1 (-0.5 to 0.9)

-0.20 (-0.41 to 0.02)

Index Tibia (n = 76)

8.8 (3.9 to 14.3)

0.5 (-0.3 to 1.7)

-0.14 (-0.35 to 0.09)

Non-index Femur (n = 33)

2.6 (1.6 to 8.2)

0.4 (-0.2 to 1.6)

-0.06 (-0.40 to 0.29)

Non-index Tibia (n = 30)

1.1 (0.6 to 3.9)

0.2 (-0.1 to 1.2)

-0.27 (-0.57 to 0.10)

  1. No Spearman correlation coefficients were statistically significant. 95% CI = 95% confidence interval of the median or 95% confidence interval of the Spearman Correlation. See Additional File 1 for scatter plots of the analyzed correlations.