Figure 4

Measurements of approximate BML volume based on only the coronal and sagittal images with the largest area of signal abnormality may misrepresent the greatest diameter of a BML. Image 10, image with the largest BML area, would traditionally be measured to approximate BML volume and result in an anterior-posterior diameter of 1.2 cm but with the newer technique, measuring across images (including images 9 and 11), the anterior-posterior diameter is 1.5 cm. The white circles indicate areas of increased signal intensity beyond the dimensions indicated on image 10. The image contrast is optimized for measuring bone marrow lesions based on the measurement protocol (not for viewing other anatomical structures).