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Table 2 A list of known genes in the top 30 genes most highly expressed in the normal cartilage and the regenerated tissues harvested at 2 and 4 weeks.

From: Gene expression profile of the cartilage tissue spontaneously regenerated in vivo by using a novel double-network gel: Comparisons with the normal articular cartilage

Tissue

Place

Gene

Regenerated (2 Wks.)

2

Pro alpha1 type II collagen

 

3

Signalosome subunit 6

 

4

Luteinizing hormone beta polypeptide

 

6

Pro alpha1 type II collagen

 

8

COL3A1 protein isoform 9

 

12

Proteoglycan 4

 

14

Peroxisome proliferator-activated receptor delta (PPARD)

 

18

Pleckstrin homology domain containing, family A member 4

 

21

Transcription factor CP2

 

22

Cbp/p300-interacting transactivator

 

23

Type II Collagen

 

27

COL3A1 protein, transcript variant 3

 

28

Matrix Gla protein

Regenerated (4 Wks.)

1

Luteinizing hormone beta polypeptide

 

2

COL3A1 protein isoform 9

 

3

Pro alpha1 type II collagen

 

5

Pro alpha1 type II collagen

 

6

Signalosome subunit 6

 

13

Type II Collagen

 

14

Cbp/p300-interacting transactivator

 

15

Transcription factor CP2

 

16

Proteoglycan 4

 

19

Matrix Gla protein

 

20

COL3A1 protein, transcript variant 3

 

22

Matrix Gla protein

 

23

Tetraspan NET-6

Normal cartilage

1

T-cell Receptor gamma chain V1.1

 

2

Mindbomb homolog 2

 

3

Signalosome subunit 6

 

10

Pleckstrin homology domain containing, family A

 

15

Matrix Gla protein

 

20

Spectrin, beta, non-erythrocytic 2

 

21

Glutathione synthetase

 

22

Peroxisome proliferator-activated receptor delta

 

23

Brain protein I3

 

29

Pro alpha1 type II collagen

 

30

Immunoglobulin heavy chain VDJC-alpha (IgA)