Skip to main content

Table 2 Baseline characteristics of participants who completed 2 year follow up

From: Effects of Hylan G-F 20 supplementation on cartilage preservation detected by magnetic resonance imaging in osteoarthritis of the knee: a two-year single-blind clinical trial

  Intervention
n = 25
Control
n = 30
P value*
Age, years 61.6 (9.4) 61.3 (9.5) 0.89
Females, number (%) 15 (60) 12 (40) 0.14†
Body mass index, kg/m2 30.3 (3.9) 28.9 (4.5) 0.23
Kellgren-Lawrence grade, number (%)    0.10
2 16 (64) 25 (83)  
3 9 (36) 5 (17)  
Joint space narrowing, number (%) 24 (96) 29 (97) 0.90
Medial tibial cartilage volume, mm3 1488 (540) 1439 (619) 0.76
Lateral tibial cartilage volume, mm3 1485 (748) 1881 (720) 0.05
Medial tibial plateau bone area, mm2 2359 (415) 2503 (515) 0.27
Lateral tibial plateau bone area, mm2 1738 (325) 1827 (409) 0.38
Medial tibiofemoral cartilage defect score 4 [1, 8] 6 [1, 8] 0.08§
Lateral tibiofemoral cartilage defect score 4 [1, 8] 2.5 [0, 8] 0.23§
Prevalence of medial tibiofemoral bone marrow lesions, number (%)** 9 (38) 18 (72) 0.02†
Prevalence of lateral tibiofemoral bone marrow lesions, number (%)** 7 (29) 8 (32) 0.83†
  1. Data were reported as mean (SD), median [range], or number (%)
  2. *for difference between intervention and control groups using independent samples t test, Mann-Whitney U test§, or chi-squared test† where appropriate
  3. **Bone marrow lesion data available in 24 subjects of intervention group and 25 subjects of control group who completed 24 month follow up