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Table 2 Parameters for trabecular bone were measured below the growth plate at the proximal metaphysis of the tibia in Toluidine-Blue and calcein double-labeled sections.

From: Hyperadiponectinemia enhances bone formation in mice

  WT Ad-Tg Line 11 Ad-Tg Line 13
BV/TV (%) 12.6 ± 2.7 16.1 ± 2.5* 17.3 ± 1.7**
Tb.N (/mm) 3.3 ± 0.3 3.9 ± 0.4* 3.9 ± 0.5*
OS/BS (%) 7.1 ± 4.1 17.7 ± 4.9** 15.4 ± 3.5*
O.Th (μm) 2.8 ± 0.2 3.3 ± 0.1** 2.8 ± 0.2
Ob.S/BS (%) 3.3 ± 2.8 7.4 ± 2.2* 9.3 ± 5.4**
N.Oc/B.Pm (/100 mm) 123.7 ± 41.1 112.2 ± 41.8 132.1 ± 60.7
Oc.S/BS (%) 1.0 ± 0.5 1.1 ± 0.7 1.4 ± 0.5
ES/BS (%) 2.7 ± 1.4 3.3 ± 1.5 4.4 ± 1.1
MAR (μm/day) 1.4 ± 0.2 1.7 ± 0.1** 1.6 ± 0.1*
MS/BS (%) 19.1 ± 3.2 33.1 ± 2.9** 26.8 ± 5.2*
BFR/BS (mm3/mm2/year) 0.09 ± 0.02 0.18 ± 0.03** 0.14 ± 0.03**
dLS/BS (%) 7.0 ± 1.0 20.7 ± 2.0** 14.6 ± 4.2**
  1. BV/TV, bone volume/total tissue volume; Tb. N, trabecular number; OS/BS, osteoid surface/bone surface; O.Th, osteoid thickness; Ob.S/BS, osteoblast surface/bone surface; N.Oc/B.Pm, osteoclast number/bone perimeter; Oc.S/BS, osteoclast surface/bone surface; ES/BS, eroded surface/bone surface; MAR, mineral apposition rate; MS/BS (mineralization ratio), mineralizing surface/bone surface; BFR/BS, bone formation rate/bone surface; dLS/BS, double labeled surface/bone surface. Data are expressed as means ± S.D. of 8 bones/group. *P < 0.05, **P < 0.01, significantly different from WT mice.
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