Skip to main content
Figure 8 | BMC Musculoskeletal Disorders

Figure 8

From: Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage

Figure 8

TN-C vs. ARG-aggrecan release in the rat meniscal tear model. A, Time course of TN-C vs. ARG-aggrecan release. Rats were euthanized at different times after surgery (4 days, 1 wk, 2 wks, and 3 wks; n = 10 rats/time point). Five naïve rats (10 joints) per time point were included. For each time point, 10 synovial fluid lavage samples from the right meniscal tear (MT), left contra-lateral (CT), and naïve (left +right knees) joints were tested for TN-C and ARG-aggrecan and values corrected for dilution using serum urea levels. Average values are shown with the error bars indicating SD. B, Correlation analysis of TN-C vs. ARG-aggrecan release in the rat meniscal tear model. TN-C and ARG-aggrecan data from the first five animals (n = 5 MT right knees and 5 CT left knees) of each time point (4 days, 1 wk, 2 wks, and 3 wks) were plotted in a correlation plot. Circles represent values from the CT knees and crosses represent values from the MT knees (n = 40 CT and 40 MT).

Back to article page