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Table 7 Haplotype frequencies of PAI-1 gene polymorphisms between ONFH patients (n = 206) and controls (n = 251)

From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

  Haplotype Frequency   
  rs2227631 rs1799889 rs11178 Controls Patients OR (95% CI) p
Hap1a G 5G T 0.391 0.310 1* -
Hap2 A 4G C 0.305 0.398 1.63(1.31-2.02) <0.001
Hap3 G 4G C 0.113 0.103 1.14(0.83-1.55) 0.425
Hap4 G 4G T 0.115 0.092 0.98(0.71-1.34) 0.875
  1. aHaplotype G-5G-T (Hap1) was chosen to be the baseline haplotype; *reference category (odds ratio, 1.0)