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Table 5 Genotype frequencies of PAI-1 gene polymorphisms between ONFH patients and controls in men and women

From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

   Men Women
Position Genotype Controls Patients p Controls Patients p
g.-844G/A GG 92(47.7) 53(33.3) 0.025 24(41.4) 14(29.8) 0.386
(rs2227631) GA 71(36.8) 74(46.5)   26(44.8) 23(48.9)  
  AA 30(15.5) 32(20.1)   8(13.8) 10(21.3)  
g.-6754G/5G 5G5G 37(19.2) 21(13.2) 0.030 9(15.5) 8(17.0) 0.976
(rs1799889) 4G5G 102(52.8) 73(45.9)   28(48.8) 22(46.8)  
  4G4G 54(28.0) 65(40.9)   21(36.2) 17(36.2)  
g.10700C/T TT 62(32.1) 33(20.8) 0.003 17(29.3) 12(25.5) 0.718
(rs11178) CT 91(47.2) 69(43.4)   25(43.1) 24(51.1)  
  CC 40(20.7) 57(35.8)   16(27.6) 11(23.4)