Table 5 Genotype frequencies of PAI-1 gene polymorphisms between ONFH patients and controls in men and women
From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head
Men | Women | ||||||
|---|---|---|---|---|---|---|---|
Position | Genotype | Controls | Patients | p | Controls | Patients | p |
g.-844G/A | GG | 92(47.7) | 53(33.3) | 0.025 | 24(41.4) | 14(29.8) | 0.386 |
(rs2227631) | GA | 71(36.8) | 74(46.5) | 26(44.8) | 23(48.9) | ||
AA | 30(15.5) | 32(20.1) | 8(13.8) | 10(21.3) | |||
g.-6754G/5G | 5G5G | 37(19.2) | 21(13.2) | 0.030 | 9(15.5) | 8(17.0) | 0.976 |
(rs1799889) | 4G5G | 102(52.8) | 73(45.9) | 28(48.8) | 22(46.8) | ||
4G4G | 54(28.0) | 65(40.9) | 21(36.2) | 17(36.2) | |||
g.10700C/T | TT | 62(32.1) | 33(20.8) | 0.003 | 17(29.3) | 12(25.5) | 0.718 |
(rs11178) | CT | 91(47.2) | 69(43.4) | 25(43.1) | 24(51.1) | ||
CC | 40(20.7) | 57(35.8) | 16(27.6) | 11(23.4) | |||