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Table 4 Genotypes and allelic frequencies of PAI-1 gene polymorphisms between ONFH subtype patients (n = 206) and controls (n = 251)

From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

    Patients p
Position Genotype Controls Idia Alcb Stec vs Idi Alc Ste
g.-844G/A G 329(65.5) 107(54.6) 83(57.6) 41(56.9) 0.007 0.082 0.154
(rs2227631) A 173(34.5) 89(45.4) 61(42.4) 31(43.1)    
  GG+GA 213(84.9) 75(76.5) 61(84.7) 28(77.8) 0.066 0.977 0.279
  AA 38(15.1) 23(23.5) 11(15.3) 8(22.2)    
g.-6754G/5G 5G 222(44.2) 76(38.8) 50(34.7) 27(37.5) 0.191 0.042 0.282
(rs1799889) 4G 280(55.8) 120(61.2) 94(65.3) 45(62.5)    
  4G5G+5G5G 176(70.1) 61(62.2) 41(56.9) 22(61.1) 0.157 0.036 0.274
  4G4G 75(29.9) 37(37.8) 31(43.1) 14(38.9)    
g.10700C/T T 274(54.6) 88(44.9) 62(43.1) 33(45.8) 0.021 0.015 0.164
(rs11178) C 228(45.4) 108(55.1) 82(56.9) 39(54.2)    
  TT+CT 195(77.7) 66(67.3) 47(65.3) 25(69.4) 0.046 0.032 0.274
  CC 56(22.3) 32(32.7) 25(34.7) 11(30.6)    
  1. aidiopatic ONFH; balcohol-induced ONFH; csteroid-induced ONFH