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Table 5 Overview of PMMA-studies in the last 20 years

From: Polymethylmethacrylate-assisted ventral discectomy: Rate of pseudarthrosis and clinical outcome with a minimum follow-up of 5 years

Author, Year Study design, follow-up Material No. of patients Clinical outcome Fusion according to author Re-OP
Böker et al., 1989[15] Retrospective
15-20 years
PMMA 57 not assessed 89% 0
Samii et al., 1989[16] Retrospective
4.8 years
PMMA 438 81% pain relief not assessed 35 (8%)
van den Bent et al., 1996[7] Prospective
2 years
PMMA
MDO
42
39
70% good
77% good
28%
63%
0
0
Hamburger et al., 2001[8] Retrospective
12.2 years
PMMA 249 77.5% exc. or good 53.8% 24 (9.6%)
Jöllenbeck et al., 2001[10] Prospective
7 days
PMMA
TTC
100
100
81% compl. recovery
78% "
not assessed 1 (1%)
1 (1%)
Bärlocher et al., 2002[1] Prospective
1 year
MDO
ABG
PMMA
TTC
33
30
26
36
75.5% exc. or good
80% "
87.5% "
94.4% "
93.3%
65.3%
0%
97.2%
2 (6.1%)
1 (3.3%)
0
0
Chen et al., 2005[18] Prospective
2 years
PMMA-cage 63 100% exc. or good 100% 0
Korinth et al., 2006[17] Retrospective
6 years
PMMA 124 93.6% exc. or good not assessed 3 (2.4%)
Schröder et al., 2007[5] Prospective
2 years
PMMA
TTC
53
54
85% exc. or good
77.7% "
66%
87%
0
0
  1. Overview of studies in the last 20 years evaluating the outcome of patients with DDD treated with ventral discectomy and PMMA-assisted fusion.
  2. MDO = Microdiscetomy only; ABG = autologous bone graft; TTC = titanium cage