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Table 5 Overview of PMMA-studies in the last 20 years

From: Polymethylmethacrylate-assisted ventral discectomy: Rate of pseudarthrosis and clinical outcome with a minimum follow-up of 5 years

Author, Year

Study design, follow-up

Material

No. of patients

Clinical outcome

Fusion according to author

Re-OP

Böker et al., 1989[15]

Retrospective

15-20 years

PMMA

57

not assessed

89%

0

Samii et al., 1989[16]

Retrospective

4.8 years

PMMA

438

81% pain relief

not assessed

35 (8%)

van den Bent et al., 1996[7]

Prospective

2 years

PMMA

MDO

42

39

70% good

77% good

28%

63%

0

0

Hamburger et al., 2001[8]

Retrospective

12.2 years

PMMA

249

77.5% exc. or good

53.8%

24 (9.6%)

Jöllenbeck et al., 2001[10]

Prospective

7 days

PMMA

TTC

100

100

81% compl. recovery

78% "

not assessed

1 (1%)

1 (1%)

Bärlocher et al., 2002[1]

Prospective

1 year

MDO

ABG

PMMA

TTC

33

30

26

36

75.5% exc. or good

80% "

87.5% "

94.4% "

93.3%

65.3%

0%

97.2%

2 (6.1%)

1 (3.3%)

0

0

Chen et al., 2005[18]

Prospective

2 years

PMMA-cage

63

100% exc. or good

100%

0

Korinth et al., 2006[17]

Retrospective

6 years

PMMA

124

93.6% exc. or good

not assessed

3 (2.4%)

Schröder et al., 2007[5]

Prospective

2 years

PMMA

TTC

53

54

85% exc. or good

77.7% "

66%

87%

0

0

  1. Overview of studies in the last 20 years evaluating the outcome of patients with DDD treated with ventral discectomy and PMMA-assisted fusion.
  2. MDO = Microdiscetomy only; ABG = autologous bone graft; TTC = titanium cage