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Table 2 Interference with work

From: Interference with work in fibromyalgia - effect of treatment with pregabalin and relation to pain response

 

Mean score (SD) at trial beginning

Mean score (SD) at trial end

Statistical significance

Pregabalin dose (n)

   

Placebo (556)

6.8 (2.1)

5.6 (2.6)

****

300 mg (551)

6.7 (2.1)

5.5 (2.6)

****

450 mg (553)

6.7 (2.1)

5.3 (2.6)

****

600 mg (562)

6.7 (2.1)

5.5 (2.7)

****

Pain improvement (n)

   

Pain worse (221)

6.3 (2.2)

6.1 (2.2)

NS

0-15% (282)

7.2 (1.9)

6.5 (2.2)

****

15-30% (233)

6.8 (2.1)

5.7 (2.3)

****

30-50% (319)

6.6 (1.9)

4.2 (2.3)

****

≥50% (435)

6.6 (2.2)

3.5 (2.6)

****

VAS pain score at trial end (n)

   

>50 mm (1046)

7.0 (2.0)

6.5 (2.1)

****

>30-50 mm (326)

6.3 (2.1)

4.5 (2.0)

****

0-30 mm (387)

6.3 (2.2)

2.8 (2.3)

****

  1. Interference with work as assessed by the question "When you worked, how much did pain or other fibromyalgia symptoms interfere with your ability to do your work, including housework?" (scale 0-10) from the Fibromyalgia Impact Questionnaire. Data are presented according to daily pregabalin dose, according to improvement in pain intensity scores over the course of the trials, and according to pain state at end of the trials; abbreviations as in Table 1.