Table 3 Bone outcomes in the Fracture and BMD studies

Bone Mineral Density (BMD):

Baseline FN BMD, g/cm²

0.727 +/- 0.128

0.731 +/- 0.126

Baseline LS BMD, g/cm²

0.936 +/- 0.166

0.938 +/- 0.160

Baseline HIP BMD, g/cm²

0.880 +/- 0.151

0.885 +/- 0.146

Change BMD, over 5-years

5-year change FN BMD, g/cm²

n/a

-0.005 +/- 0.035

5-year change LS BMD, g/cm²

n/a

0.018 +/- 0.054

5-year change HIP BMD, g/cm²

n/a

-0.001 +/- 0.036

Change FN BMD, % of baseline

n/a

-0.68% +/- 5.0

Change LS BMD, % of baseline

n/a

1.9% +/- 6.0

Change HIP BMD, % of baseline

n/a

-0.11% +/- 4.2

Confirmed fragility fractures

46/795 (5.8%)

n/a