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Table 3 The Power of Our Study to Detect the Relative Risk Reduction for Pairwise Comparison of Three Pressure Groups Given Varying Control Event Rate

From: Fluid Lavage of Open Wounds (FLOW): design and rationale for a large, multicenter collaborative 2 × 3 factorial trial of irrigating pressures and solutions in patients with open fractures

   Relative risk reduction
   20% 24% 28% 32% 35%
Control event rate 25% 0.49 0.68 0.84 0.93 0.97
  27% 0.54 0.73 0.87 0.95 0.98
  30% 0.61 0.80 0.92 0.98 0.99
  33% 0.68 0.85 0.95 0.99 1.00
  35% 0.72 0.89 0.99 1.00 1.00
  1. * Note: We use a two-sided alpha level of 0.0188 for each pairwise comparison of three pressure groups, and the sample size per group at the margin is 760 (380 per cell).