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Table 3 The Power of Our Study to Detect the Relative Risk Reduction for Pairwise Comparison of Three Pressure Groups Given Varying Control Event Rate

From: Fluid Lavage of Open Wounds (FLOW): design and rationale for a large, multicenter collaborative 2 × 3 factorial trial of irrigating pressures and solutions in patients with open fractures

  

Relative risk reduction

  

20%

24%

28%

32%

35%

Control event rate

25%

0.49

0.68

0.84

0.93

0.97

 

27%

0.54

0.73

0.87

0.95

0.98

 

30%

0.61

0.80

0.92

0.98

0.99

 

33%

0.68

0.85

0.95

0.99

1.00

 

35%

0.72

0.89

0.99

1.00

1.00

  1. * Note: We use a two-sided alpha level of 0.0188 for each pairwise comparison of three pressure groups, and the sample size per group at the margin is 760 (380 per cell).