Contributions of lean mass and fat mass to bone mineral density: a study in postmenopausal women

Table 2 Determinants of bone mineral density: results of multiple linear regression analysis

Model and determinant	Bone mineral density (g/cm²)
	Lumbar spine	Femoral neck	Whole body
Model 1: Age and body weight
Age (5 years)	-0.036 (0.004)	-0.029 (0.003)	-0.032 (0.003)
Weight (5 kg)	0.027 (0.005)	0.022 (0.004)	0.016 (0.004)
R-squared	0.33	0.38	0.37
Model 2: Age and height
Age (5 years)	-0.032 (0.005)	-0.028 (0.003)	-0.029 (0.003)
Height (5 cm)	0.027 (0.008)	0.012 (0.006)	0.016 (0.006)
R-squared	0.29	0.30	0.34
Model 3: Age, body weight, height
Age (5 years)	-0.034 (0.004)	-0.030 (0.003)	-0.031 (0.003)
Weight (5 kg)	0.023 (0.006)	0.024 (0.004)	0.015 (0.004)
Height (5 cm)	0.012 (0.008)	-0.005 (0.006)	0.006 (0.006)
R-squared	0.34	0.38	0.37
Model 4: Age and BMI
Age	-0.039 (0.004)	-0.032 (0.003)	-0.034 (0.003)
BMI	0.031 (0.008)	0.032 (0.058)	0.019 (0.006)
R-squared	0.30	0.37	0.35
Model 5: Age, lean mass, fat mass
Age (5 years)	-0.036 (0.004)	-0.029 (0.003)	-0.030 (0.003)
Lean mass (5 kg)	0.034 (0.011)	0.031 (0.008)	0.036 (0.008)
Fat mass (5 kg)	0.022 (0.009)	0.017 (0.007)	0.001 (0.006)
R-squared	0.33	0.38	0.39
Model 6: Age, lean mass index, fat mass index*
Age (5 years)	-0.039 (0.004)	-0.033 (0.003)	-0.033 (0.003)
Lean mass index (kg/m²)	0.010 (0.006)	0.014 (0.004)	0.015 (0.004)
Fat mass index (kg/m²)	0.009 (0.004)	0.008 (0.003)	0.000 (0.003)
R-squared	0.29	0.36	0.36

Notes: All bolded figures indicate that the association was statistically significant at p < 0.05 level. (1) lean mass index = lean mass/height², and fat mass index = fat mass/height² (see Methods section).

ISSN: 1471-2474