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Table 3 Association between quantitative ultrasound (QUS) parameters and hormonal factors

From: Menstrual irregularity and bone mass in premenopausal women: Cross-sectional associations with testosterone and SHBG

 

Unadjusted model

Adjusted model

 

(n = 382)

β (95% CI)

Model 1 (n = 358)

β (95% CI)

Model 2 (n = 358)

β (95% CI)

BUA

   

Testosterone

0.15 (0.04, 0.24)

0.14 (0.04, 0.25)

0.13 (0.03, 0.24)

SHBG

-0.14 (-0.24, -0.04)

-0.07 (-0.19, 0.05)

-0.05 (-0.17, 0.06)

FAI

0.18 (0.08, 0.28)

0.14 (0.03, 0.26)

0.13 (0.01, 0.24)

SOS

   

Testosterone

0.11 (0.01, 0.21)

0.13 (0.03, 0.24)

0.12 (0.02, 0.23)

SHBG

-0.13 (-0.23, -0.03)

-0.16 (-0.27, -0.04)

-0.14 (-0.26, -0.02)

FAI

0.16 (0.06, 0.26)

0.20 (0.08, 0.31)

0.18 (0.06, 0.29)

QUI

   

Testosterone

0.12 (0.02, 0.22)

0.14 (0.03, 0.24)

0.13 (0.02, 0.23)

SHBG

-0.14 (-0.24, -0.04)

-0.13 (-0.25, -0.01)

-0.11 (-0.23, 0.01)

FAI

0.17(0.07, 0.27)

0.18 (0.07, 0.29)

0.16 (0.05, 0.28)

  1. BUA = broadband ultrasound attenuation. SOS = speed of sound. QUI = quantitative ultrasound index. SHBG = sex hormone-binding globulin. FAI = free androgen index. QUS measures and hormonal parameters were log transformed before converted into standardized variables. β = standardised beta coefficients. Model 1 adjusted for age, BMI and smoking. Model 2 further adjusted for menstrual cycle pattern. Bold denotes significant association (P < 0.05).