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Figure 2 | BMC Musculoskeletal Disorders

Figure 2

From: Enhancement of antinociception by coadminstration of minocycline and a non-steroidal anti-inflammatory drug indomethacin in naïve mice and murine models of LPS-induced thermal hyperalgesia and monoarthritis

Figure 2

Lipopolysaccharide (LPS)-induces thermal hyperalgesia in BALB/c mice. Time course of the reaction latency time to the hot plate test after administration of LPS (1 mg/kg, n = 5, i.p.) or its vehicle (n = 8). Each point represents the mean ± S.E.M of the values obtained from 5-8 animals. Statistically significant differences in comparison with drug vehicle at the same time point post treatment: * p < 0.05 and ** p < 0.01 (two-way ANOVA followed by Bonferroni test).

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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