Change of JSW and osteophyte score during the follow-up period. A and B. Distribution of the JSW narrowing rate (A) and increase in osteophyte score (B) among evaluated knee joints. C and D. Distribution of the increase of osteophyte score among non-progressed (C) and progressed joints (D). E. Increase in osteophyte score relative to JSW narrowing rate. Results are shown by mean + SD. *, P < 0.05, unpaired t-test. In C-E, open and solid bars indicate non-progressed and progressed joints, respectively.