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Table 2 Top 30 Relative risks of co-morbidities in patients with rheumatoid arthritis 16 years and older as compared with control group (N = 61,591 for each group)

From: Data-driven identification of co-morbidities associated with rheumatoid arthritis in a large US health plan claims database

ICD9

Co-morbidity Condition

Persons with RA (N)

Percent

RR

95% CI

6960

Psoriatic arthropathy

1,540

2.5%

12.3

10.5-15.1

99529

Adverse effect medicinal and biologic substance NEC/NOS

360

0.6%

7.7

5.7-10.4

99666

Reaction-internal joint prosthesis

131

0.2%

4.0

2.7-5.8

9952

Unspecified adverse effect drug, medicinal and biol substance properly administered

717

1.2%

3.9

3.4-4.7

73309

Osteoporosis NEC

479

0.8%

3.9

3.2-4.8

5163

Idiopathic fibrosing alveolitis

205

0.3%

3.9

2.9-5.2

73027

Osteomyelitis NOS-ankle

148

0.2%

3.5

2.5-5.0

2793

Immunity deficiency NOS

81

0.1%

3.4

2.1-5.3

7901

Elevated sediment rate

171

0.3%

3.3

2.4-4.5

7955

Tuberculin test reaction abnormal or positive

239

0.4%

3.3

2.5-4.3

99520

Adverse effect medicinal and biologic substance NOS

708

1.1%

3.2

2.8-3.8

73020

Osteomyelitis NOS-unspec

119

0.2%

3.1

2.2-4.5

28529

Anemia-of other chronic illness

415

0.7%

3.1

2.6-3.8

2550

Cushing's syndrome

61

0.1%

3.0

1.8-5.1

515

Postinflammatory pulmonary fibrosis

1,221

2.0%

3.0

2.7-3.4

2841

Pancytopenia

80

0.1%

3.0

1.9-4.6

4920

Emphysematous BLEB

72

0.1%

2.9

1.8-4.5

79579

Other and unspecified nonspecific immunologic findings

373

0.6%

2.8

2.3-3.5

2794

Autoimmune disease NEC

142

0.2%

2.8

2.1-3.9

5369

Stomach function disorder NOS

67

0.1%

2.8

1.8-4.4

4430

Raynaud's syndrome

251

0.4%

2.8

2.2-3.5

53130

Acute stomach ulcer NOS

76

0.1%

2.7

1.8-4.2

70709

Decubitus ulcer, site NEC

97

0.2%

2.7

1.8-4.0

8082

Fracture of pubis-closed

136

0.2%

2.7

1.9-3.7

27549

Disorders of calcium metabolism NEC

69

0.1%

2.6

1.7-4.2

73340

Aseptic necrosis bone NOS

75

0.1%

2.6

1.7-4.0

8088

Pelvic fracture NOS-closed

121

0.2%

2.6

1.8-3.6

73007

Acute osteomyelitis-ankle

77

0.1%

2.6

1.7-3.9

4476

Arteritis NOS

247

0.4%

2.5

2.0-3.2

73302

Idiopathic osteoporosis

182

0.3%

2.5

1.9-3.3

  1. * Aged at least 16 years, matched controls with Dermatitis/Eczema diagnosis.
  2. Only includes conditions for which there were at least 20 controls Excluded Arthritis/RA-related codes ICD 710-729;996.4.
  3. NOS: Not otherwise specified NEC: Not elsewhere classified