Apoptotic cell number after ARG098 treatment in RA synovium implanted in SCID mice. Apoptotic cell numbers were counted and are expressed as the cell number in a field. The white bars show the apoptotic cell number in the collagen tissue. The black bars show the apoptotic cell number in the lymph follicle. Statistical analyses of cell number in the lymph follicle were performed with Dunnett's test and p values are shown in the figure. Analysis of the collagen tissue was performed with Steel's test. *, p < 0.05 versus 0 μg/mouse group.