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Figure 2 | BMC Musculoskeletal Disorders

Figure 2

From: ARG098, a novel anti-human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient-HuRAg mouse model

Figure 2

Cytotoxic effect of ARG098 on RA synoviocytes preincubated with inflammatory cytokines. RA synoviocytes (RASC) from five patients were preincubated with 5 ng/mL of tumor necrosis factor (TNF)-α or 0.5 ng/mL of interleukine (IL)-1β for 5 days and then treated with 100 ng/mL of ARG098 for 24 h. N, non-pretreated group. Each bar represents mean ± SEM (n = 6). Cytotoxicity was measured with the WST assay.

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