Analysis of meniscal degeneration and meniscal gene expression

Table 5 Differential gene expression confirmed by real time RT-PCR*

Gene name	Gene ID	Differential Expression* Microarray	Differential Expression* RT-PCR	Description
HLA-DPA1	M27487	5.3	10.5	Major histocompatibility complex, class II, DP alpha
ITGB2	NM_000211	6.6	5.2	Integrin, beta 2
PTGES	AF010316	3.2	3.4	Prostaglandin E synthase
ENPP1	BF057080	1.7	2.1	Ectonucleotide pyrophosphatase/phosphodiesterase 1
ADAMTS5	BI254089	1.7	1.9	ADAM metallopeptidase with thrombospondin type 1 motif, 5
IL26	NM_018402	1.7	4.3	Interleukin 26
TUFT1	NM_020127	2.8	3.9	Matrix metalloproteinase 1
MMP10	NM_002425	-2.7	-3.1	Matrix metalloproteinase 10

*Differential Expression -- the numbers are the ratio of the relative expression level of a specific gene in OA1 meniscal cells to the relative expression level of the specific gene in the control meniscal cells (mixture of RNA prepared from the three normal control meniscal cells).

ISSN: 1471-2474