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Table 5 Differential gene expression confirmed by real time RT-PCR*

From: Analysis of meniscal degeneration and meniscal gene expression

Gene name Gene ID Differential Expression* Microarray Differential Expression* RT-PCR Description
HLA-DPA1 M27487 5.3 10.5 Major histocompatibility complex, class II, DP alpha
ITGB2 NM_000211 6.6 5.2 Integrin, beta 2
PTGES AF010316 3.2 3.4 Prostaglandin E synthase
ENPP1 BF057080 1.7 2.1 Ectonucleotide pyrophosphatase/phosphodiesterase 1
ADAMTS5 BI254089 1.7 1.9 ADAM metallopeptidase with thrombospondin type 1 motif, 5
IL26 NM_018402 1.7 4.3 Interleukin 26
TUFT1 NM_020127 2.8 3.9 Matrix metalloproteinase 1
MMP10 NM_002425 -2.7 -3.1 Matrix metalloproteinase 10
  1. *Differential Expression -- the numbers are the ratio of the relative expression level of a specific gene in OA1 meniscal cells to the relative expression level of the specific gene in the control meniscal cells (mixture of RNA prepared from the three normal control meniscal cells).