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Table 4 Genes differentially expressed in individual OA meniscal cells compared to normal meniscal cells.

From: Analysis of meniscal degeneration and meniscal gene expression

Gene

Name

Gene ID

OA1

OA1

OA3

OA4

OA5

Description

BST1

NM_004334

3.9

3.4

3.3

1.6

2.2

bone marrow stromal cell antigen 1

FGF9

NM_002010

3.7

2.4

3.7

2.5

2.9

Fibroblast growth factor 9

ACAN

NM_013227

2.4

1.6

1.6

0.0

1.6

Aggrecan

COL11A1

J04177

0.0

11.5

5.8

2.2

3.6

Collagen, type XI, alpha 1

ANKH

AL833238

0.0

1.8

1.7

1.5

1.8

Ankylosis, progressive homolog (mouse)

MGP

NM_000900

11.8

4.7

21.6

0.0

17.6

Matrix Gla protein

TUFT1

NM_020127

2.8

2.7

1.9

0.0

0.0

Tuftelin 1

TFIP11

NM_012143

2.2

1.6

0.0

0.0

0.0

Tuftelin interacting protein 11

IL20RB

AL578102

2.3

2.7

0.0

2.6

7.8

Interleukin 20 receptor beta

IL26

NM_018402

1.7

1.6

1.6

0.0

3.0

Interleukin 26

COL4A5

AW052179

-3.1

-3.0

-3.1

-3.0

-3.1

Collagen, type IV, alpha 5 (Alport syndrome)

MMP9

NM_004994

-2.2

-2.1

-2.1

0.0

-2.2

Matrix metallopeptidase 9

MMP10

NM_002425

-2.7

-2.6

-2.7

-1.5

-2.6

Matrix metallopeptidase 10

MMP12

NM_002426

-2.1

-2.0

-2.1

0.0

-2.1

Matrix metallopeptidase 12

FZD10

NM_007197

-1.6

-1.5

-1.6

-1.5

-1.5

Frizzled homolog 10 (Drosophila)

CYTL1

NM_018659

-2.6

-2.6

-2.6

-2.6

-2.5

Cytokine-like 1

CHODL

NM_024944

-2.6

-2.6

-2.6

 

-2.6

Chondrolectin

  1. *Positive number indicates elevated expression (fold) in OA meniscal cells compared to normal meniscal cells. Negative number indicates decreased expression (fold) in OA meniscal cells compared to normal meniscal cells. 0.0 indicates there was no differential gene expression being detected.