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Table 1 Modified Mankin score for evaluating the severity of cartilage damage.

From: The influence of long-term treadmill exercise on bone mass and articular cartilage in ovariectomized rats

Variable

Score

Surface

0 = normal

 

1 = irregular

 

2 = fibrillated/vaculoated

 

3 = clefts/erosion

Cellularity

0 = normal

 

1 = slight decrease in chondrocytes

 

2 = marked decrease in chondrocytes

 

3 = no cells

Staining

0 = normal

 

1 = little decrease in staining

 

2 = marked decrease in staining

 

3 = no staining

Cloning

0 = normal

 

1 = occasional doublets

 

2 = doublets and triplets

 

3 = multiple nested cells

  1. Note: The maximal score is 12 points. Higher score means higher degree of cartilage degeneration.