Figure 3
Expression of muscle-specific miRNAs using quantitative real-time PCR. After entrapment, the expression of miR-1 and miR-133 was significantly decreased to ~50% of those observed in the sham control group at 3 and 6 months after entrapment. After decompression, miR-1 and miR-133a levels were unchanged and sustained a significant decrease at 1 and 3 months later, respectively. There were no statistical differences in the expression of miR-206 at the indicated time points after nerve entrapment and after decompression. Bars represent means ± standard error of 6 independent experiments; *, P < 0.05 vs. sham control.