|
Variable Measured
|
Cohort 1
|
Cohort 2
|
Cohort 3
|
|---|
| |
(N = 4)*
|
(N = 4)
|
(N = 13)
|
|---|
| |
Visit 1
|
Visit 2
|
P**
|
Visit 1
|
Visit 2
|
P
|
Visit 1
|
Visit 2
|
P
|
|---|
|
BP Syst (mm Hg)
|
136 ± 9.3
|
128 ± 9.9
|
0.40
|
144 ± 7.8
|
141 ± 3.5
|
0.80
|
138 ± 5.7
|
142 ± 5.4
|
0.39
|
|
BP Diast (mm Hg)
|
83 ± 6.6
|
82 ± 5.5
|
0.86
|
78 ± 10.1
|
88 ± 3.7
|
0.46
|
96 ± 2.3
|
88 ± 3.4
|
0.04
|
|
HR (BPM)
|
69 ± 4.2
|
77 ± 4.6
|
0.01
|
74 ± 9.2
|
76 ± 9.4
|
0.74
|
72 ± 3.7
|
71 ± 4.3
|
0.65
|
|
WBC† (cell/mm3)
|
6.1 ± 0.6
|
6.1 ± 0.3
|
0.48
|
6.6 ± 1.2
|
5.9 ± 0.9
|
0.20
|
6.9 ± 0.5
|
6.6 ± 0.2
|
0.34
|
|
Hgb (g/dL)
|
12.8 ± 0.8
|
12.6 ± 0.7
|
0.23
|
14.4 ± 0.9
|
14.5 ± 0.8
|
0.25
|
14.6 ± 0.2
|
14.1 ± 0.3
|
0.02
|
|
Creatinine (mg/dL)
|
0.78 ± 0.08
|
0.78 ± 0.07
|
1
|
0.68 ± 0.11
|
0.70 ± 0.11
|
0.39
|
0.83 ± 0.04
|
0.84 ± 0.04
|
0.67
|
|
AST (U/L)
|
17.3 ± 1.8
|
17.8 ± 0.5
|
0.81
|
24.0 ± 3.5
|
25.0 ± 5.0
|
0.57
|
21.9 ± 2.4
|
22.3 ± 2.4
|
0.86
|
- * Patients included in this analysis were those receiving chicory who had lab values available at both baseline and final visits. Values represent mean and S.E.M.
- ** P values calculated using paired t-test, V1 vs V2.
-
†Normal range: WBC 4.1-11.1 × 10/μL.
