Table 1 Demographic and disease features at baseline in 3 cohorts

Age (years)

59 ± 2

64 ± 4

65 ± 2

0.28

Gender F/M

9/0 (100%)

5/3 (62.5%)

16/7 (70%)

0.133

Non-Hispanic Caucasian

67%

75%

91%

0.21

BMI

35.3 ± 4.6

30.4 ± 1.6

29.6 ± 1.2

0.20

Knee/Hip

8/1

5/3

20/3

0.60

Walking Time (sec)

12.0 ± 2.6

7.3 ± 0.7

7.7 ± 0.4

0.009

WOMAC Item #1

3.2 ± 0.3

2.4 ± 0.3

3.9 ± 0.4

0.075

WOMAC Item #5

3.2 ± 0.3

2.4 ± 0.3

2.4 ± 0.2

0.047

BPI **

5.6 ± 0.9

2.6 ± 0.7

3.9 ± 0.4

0.19

Global VAS (mm)

54.5 ± 10.9

31.0 ± 6.7

45.8 ± 4.4

0.15

Modified HAQ (0-3 scale)

1.4 ± 0.2

0.7 ± 0.1

0.8 ± 0.1

0.17

Hemoglobin (g/dL)^†

13.0 ± 0.5

14.2 ± 0.4

14.4 ± 0.2

0.016

Creatinine (mg/dL)^†

0.77 ± 0.06

0.80 ± 0.09

0.82 ± 0.03

0.74

AST (U/L)^†

19 ± 1

23 ± 2

24 ± 2

0.32