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Figure 5 | BMC Musculoskeletal Disorders

Figure 5

From: Hind limb unloading of mice modulates gene expression at the protein and mRNA level in mesenchymal bone cells

Figure 5

Changes in the pattern of expression of genes involved in bone homeostasis (Stro1, CXCL12 and CXCR4) induced by HU, and their reversibility. Gene expression analyzed by immunohistochemistry for Stro1, CXCL12 and by in situ hybridization for CXCR4. Description as in legend of Figure 2. For micrographs missing from the panel see legend Figure 3. Control for immunohistochemistry, without primary antibody, and for in situ hybridization, here with sense probe for MT1-MMP, are shown respectively in the second and fourth panel from the top.

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