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Table 6 Large or small MRI signal as a surrogate marker for CNS lupus in 25 SLE patients

From: Diagnostic reliability of magnetic resonance imaging for central nervous system syndromes in systemic lupus erythematosus: a prospective cohort study

   Clinical outcome of CNS syndrome  
MRI signal size MRI change Improve Stabilize or deteriorate p
Large Improve 4 0 0.029
  Stabilize or deteriorate 0 3  
Small Improve 2 0 1.000
  Stabilize or deteriorate 13 3  
  1. *P values were determined by Fisher's exact test.
  2. †Large MRI signal size = ø ≥ 10 mm; Small MRI signal size = ø < 10 mm, mostly ø < 5 mm
  3. CNS: central nervous system; MRI: magnetic resonance imaging; SLE: systemic lupus erythematosus; PPV: positive predictive value; NPV:negative predictive value