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Table 4 Large MRI signal as a diagnostic tool for CNS lupus in 191 patients with SLE

From: Diagnostic reliability of magnetic resonance imaging for central nervous system syndromes in systemic lupus erythematosus: a prospective cohort study

 

Large signal

Negative or small signal

Relative risk

(95% CI)

p

PPV

NPV

CNS group

7 (12%)

50 (88%)

3.7 (2.9 - 4.7)

0.0002

1.000

0.728

   Neurologic Disorders

5 (15%)

29 (85%)

5.6 (4.0 - 7.8)

0.0003

1.000

0.822

   Psychiatric Disorders

5 (14%)

31(86%)

5.3 (3.9 - 7.3)

0.0003

1.000

0.812

Non-CNS group

0 (0%)

134 (100%)

-

-

-

-

  1. *Abnormal MRI signals were classified into large (ø ≥ 10 mm) or small abnormal MRI signals (ø < 10 mm).
  2. P values were determined by Fisher's exact test and CNS group or its subgroup is compared with non-CNS group.
  3. CI: Confidence Interval; PPV: positive predictive value; NPV: negative predictive value