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Table 4 Large MRI signal as a diagnostic tool for CNS lupus in 191 patients with SLE

From: Diagnostic reliability of magnetic resonance imaging for central nervous system syndromes in systemic lupus erythematosus: a prospective cohort study

  Large signal Negative or small signal Relative risk
(95% CI)
p PPV NPV
CNS group 7 (12%) 50 (88%) 3.7 (2.9 - 4.7) 0.0002 1.000 0.728
   Neurologic Disorders 5 (15%) 29 (85%) 5.6 (4.0 - 7.8) 0.0003 1.000 0.822
   Psychiatric Disorders 5 (14%) 31(86%) 5.3 (3.9 - 7.3) 0.0003 1.000 0.812
Non-CNS group 0 (0%) 134 (100%) - - - -
  1. *Abnormal MRI signals were classified into large (ø ≥ 10 mm) or small abnormal MRI signals (ø < 10 mm).
  2. P values were determined by Fisher's exact test and CNS group or its subgroup is compared with non-CNS group.
  3. CI: Confidence Interval; PPV: positive predictive value; NPV: negative predictive value