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Table 3 MRI as a diagnostic tool for CNS lupus in 191 patients with SLE

From: Diagnostic reliability of magnetic resonance imaging for central nervous system syndromes in systemic lupus erythematosus: a prospective cohort study

  MRI positive MRI negative Relative risk
(95% CI)
p PPV NPV
CNS Group 25 (44%) 32 (56%) 1.7 (1.1 - 2.7) 0.016 0.424 0.758
   Neurologic disorders 17 (50%) 17 (50%) 2.3 (1.3 - 4.1) 0.007 0.333 0.855
   Psychiatric disorders 16 (44%) 20 (56%) 1.9 (1.1 - 3.4) 0.038 0.320 0.833
Non-CNS Group 34 (25%) 100 (75%) - - - -
  1. *An MRI test was defined to be 'positive' when any abnormal intensity lesion was found.
  2. P values were determined by Fisher's exact test and CNS group or its subgroup is compared with non-CNS group.
  3. CI: Confidence Interval; PPV: positive predictive value; NPV: negative predictive value