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Figure 5 | BMC Musculoskeletal Disorders

Figure 5

From: Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption - implications for osteoclast quality

Figure 5

The effects of ibandronate on osteoclasts and resorption. Mature human osteoclasts were seeded on bone slices and cultured for 5 days in the presence or absence of ibandronate (Iban). A) CTX-I release measured in culture supernatants. B) Calcium release measured in culture supernatants. C) Cell viability measured by Alamar Blue. D) TRACP activity measured in culture supernatants. All results are plotted as % of control. Statistical tests were performed by ANOVA with Dunnet's multiple comparison test against the vehicle group.

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