Figure 6

3D visualization of the femorotibial subregions: Top: anterior view with the medial tibia being divided into 5 subregions (red = central, green = external, dark blue = internal, yellow = posterior, and turquoise = anterior subregion. The central subregion is defined by a cylinder and occupies 20% of the total subchondral bone area of medial tibia (MT). The weight bearing femur is divided into three strip-like subregions, each occupying 33.3% of the subchondral bone area (green = central, dark blue = internal, red = external subregion). The total subchondral bone area of the lateral tibia is shown in green and that of the lateral femur in red. Middle: oblique anterior-superior view of the subregions. Bottom: superior view onto the tibial subregions (femur not shown).